Apopka is a city in Orange County and Seminole County, Florida, United States. The population was 41,542 at the 2010 census, up from 26,969 at the 2000 census. It is part of the OrlandoKissimmeeSanford Metropolitan Statistical Area. Apopka is a Native American word for "Potato eating place". Apopka is often referred to as the "Indoor Foliage Capital of the World". The city is located in both Orange and Seminole counties, but predominantly in Orange. According to the United States Census Bureau, the city has a total area of 32.6 square miles (84.4km2). 31.2 square miles (80.9km2) of it is land and 1.4 square miles (3.5km2) of it (4.15%) is water.